For more than 60 years, the research undertaken at the Charles Darwin Foundation has focused on furthering our understanding of the natural systems, their relationship with those living in the archipelago, and the intricate and relationship with those living in the archipelago, and the intricate and delicate balance between climate, mankind, and nature. Major research efforts have also focused on the prevention, control, and eradication of invasive species to maintain Galapagos as one of the best-conserved archipelagos in the world.

The Eastern Tropical Pacific conceals extraordinary, vast deep-ocean ecosystems, plunging from oceanic islands to depths of 3,800 meter, most of which remain largely unexplored, presenting real challenges for effective protection and management. Despite their significance, these ecosystems are poorly understood and subject to persistent threats, including overfishing, climate change, pollution, and the prospect for deep-sea mining.